A prototypical heat shock protein whose overexpression is linked to carcinogenesis in humans. Source: http://www.ebi.ac.uk/ As the big data revolution continues, doctors, immunologists and other human-health oriented biologists are growing increasingly disillusioned with their ability to connect insights from large data sets to concrete human health impacts. A new review […]
Large lipid vesicles which appear similar to exosomes. Source: Wikipedia Most biologists and clinicians will be very familiar with membranous vesicles, but the concept of exosomes is less prevalent, despite being characterized 30 years ago.1 Exosomes are nanovesicles which are roughly 50 nm in size and are thought to be […]
S. aureus, cultured on an agar plate containing antibiotics. Source: CDC Public Health Image Library Drug resistant bacteria is a growing problem, claiming an estimated 23,000 deaths per year in the USA. In light of this, new research into next generation antimicrobicides has produced a therapy that holds promise in […]
A variety of treatment options exist for rheumatoid arthritis. Despite their wide availability, some patients remain untreated. How can biologics for rheumatoid arthritis help people with unmet needs? Image source: Flickr Commons The development of effective biologic drugs has brought relief to many people with chronic conditions—especially that of rheumatoid […]
Scientists have discovered a cure for MS that works in a small portion of the affected population and promises to be a tool for learning how to cure the rest. Image Source: Flickr User: SFU – University Communications A few weeks ago, the CBC (Canadian Broadcasting Corporation) broke the news […]
Viruses have played con-man to tissues and immune systems for a long time. By harnessing these capabilities, researchers are attempting to create nanoreactors and better therapeutic vehicles. Image Source: Wikimedia Commons User Splette Viruses are a non-living anomaly in the microscopic world; they make a living out of hijacking a […]
Recent developments in biologic therapies may bring an end to the off-label use of chemotherapy and other salvage therapies in hemophagocytic lymphohistiocytosis. Image Source: Wikimedia Commons user: Bill Branson Cancer may be the darling of the research world, but there are other, rarer diseases that require just as much care […]
As life science firms look for patient populations to help by designing novel biotherapeutics, they will need to ensure their research efforts allow for efficient drug discovery and development.
Companies can prepare to compete with biosimilars by adopting a simple, yet effective, strategy: innovation. By developing drugs that improve upon earlier iterations, companies can continue to protect their market advantage from lower-cost generic versions.
There is a growing need for more efficacious retinal degenerative disease treatment as the population ages and there is mounting exposure to common causes.