Protein structure of a human antibody of the IgG2 isoform generated in-vivo via VDJ recombination. Source: Wikipedia Commons As biotechs everywhere flock to to the biologic gold rush, antibody design is at the tip of everyone’s tongues. Developing effective and safe biologics is a difficult process, requiring an abundance of […]
Traditional flu vaccines have to be taken annually, and yet, are shown to be less efficient. Source: Wikimedia Commons User Grook Da Oger It’s that time of year. The temperatures are dropping, the snow is falling, and the CDC is calling for administration of the annual flu vaccine. Flu is […]
Protein structure of a human CD4 receptor. Source: European Bioinformatics Institute. While the ultimate cure or prevention strategy for HIV is still in the works, researchers continue to develop partial solutions to different aspects of the disease. These partial solutions include post exposure prophylaxis (PEP) and highly active antiretroviral […]
Acetaminophen has long been considered a safe painkiller for pregnant women, but new studies have called this into question, and more research on the subject is required. Image Credit: Flickr user Jeff Golden Acetaminophen has long been a go-to pain reliever for pregnant women. Because other common over-the-counter painkillers have […]
Molecular structure of aluminum hydroxide, the oldest and most common adjuvant added to vaccine formulations. Image source: Wikimedia With the renaissance of vaccines in full swing, advancements in adjuvant development are especially interesting. Traditional adjuvants such as alum have served effectively for decades1, but a new review has made the […]
New research insights into the neurological underpinnings of autism may provide a basis for the development of early-life pharmacological intervention strategies. Image Credit: Flickr user National Human Genome Research Institute A November 2016 study in Nature Communications has revealed new insights into the brain physiology underlying autism. It was previously […]
HIV treatment, while effective could be greatly improved by targeting something other than viral proteins. Image Source: Flickr User: snre CRISPR has been a hot topic over the past couple of years. This paradigm-shifting technique was a major contender for the Nobel Prize in Chemistry for both the 2015 and […]
The chemicals needed to produce biologics are different from those required for small molecule drug synthesis. Chemical management software can help companies overcome challenges associated with changes in reagent usage. Image Credit: Flickr use Horia Varlan Looking ahead to the future of the pharmaceutical industry, one trend is overwhelmingly clear […]
Brown fat cells, like those pictured here, are tiny thermogenesis centres in mammalian tissue. Converting white fat cells to brown ones may aid those trying to lose weight. Image Source: Wikimedia Commons User Lucasmcorso Obesity rates continue to rise throughout North America and in many places across the globe. It […]
viSNE plot of mass cytometry derived cell populations. Image Source: “viSNE enables visualization of high dimensional single-cell data and reveals phenotypic heterogeneity of leukemia, Nature Biotech.” 2013, ttp://www.c2b2.columbia.edu/danapeerlab/html/CYT/visne_figure.png Cell analysis technologies within immunology are advancing at a rapid rate and are rendering deeper data across higher volumes of cells thanks […]
