Collaborative Science

Accelerating time to market and driving innovation with collaboration, knowledge based understanding and prediction.

BIOVIA Discovery Studio

Discovery Studio is BIOVIA’s comprehensive predictive science application for the Life Sciences

Announcing BIOVIA Discovery Studio 2018

Built on BIOVIA Pipeline Pilot 2018, BIOVIA Discovery Studio 2018 stands as BIOVIA’s major release for predictive sciences and modeling and simulation in the life sciences.

  • Small Molecules affinity modeling
    • Accurately predict relative ligand binding energy for a congeneric ligand series using the new free energy perturbation (FEP) method
    • Pharmacophore screening:
      • Key Catalyst® pharmacophore protocols have been redesigned to improve performance and scalability for parallel computing
    • Rational Antibody design
      • Predict stabilizing humanized residue mutations: Predict mutations to make an antibody more human compatible without compromising antibody stability
    • Forcefield
      • Implemented the MATCH atom typing engine from the Brooks Lab for enhanced CGenFF typing support (DOI: 10.1002/jcc.21963)
      • Added the CHARMM PBEQ Poisson-Boltzmann electrostatics-based solver for enhanced representation of the electrostatic potential
      • Supports CHARMM c42b1
    • Toxicity
      • All TopKat models are now published as QMRF reports on the European Commission Joint Research Center (JRC)

System Requirements for Discovery Studio 2018

What's New in Discovery Studio 2018

With Discovery Studio you can:

  • Investigate and test hypotheses in silico prior to costly experimental implementation, thus reducing the time and expense involved in bringing products to market
  • Drive scientific exploration from target identification to lead optimization with a wealth of trusted life science modeling and simulation tools
  • Leverage an open and scalable platform to automate processes, create and deploy custom workflows, and integrate data types, databases, and third-party or in-house tools
  • Enhance personal productivity and boost team collaboration by enabling researchers to share data and make better informed decisions

Read the BIOVIA Discovery Studio Datasheet

Citations and Acknowledgements

We love to hear about Discovery Studio being used in new and interesting ways. If you want to cite the use of a BIOVIA Software product in a publication, we recommend the following format:

Ref. Dassault Systèmes BIOVIA, Discovery Studio Modeling Environment, Release 2017, San Diego: Dassault Systèmes, 2016.

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