Collaborative Science

Accelerating time to market and driving innovation with collaboration, knowledge based understanding and prediction.

BIOVIA Discovery Studio

Discovery Studio is BIOVIA’s comprehensive predictive science application for the Life Sciences

Announcing BIOVIA Discovery Studio 2020

Built on BIOVIA Pipeline Pilot 2020, BIOVIA Discovery Studio 2020 stands as BIOVIA’s major release for predictive sciences and modeling and simulation in the life sciences

  • New Multi-Site Lambda Dynamics method for rapidly calculating relative binding free energies of large congeneric libraries in early stage lead optimization.
  • New Solubility and Viscosity (SCM algorithm from MIT) formulation property prediction for biologics.
  • New Explicit membrane-based functionality adds an explicit bilayer of lipids, water and counterions to a transmembrane protein and supports MD simulation of the system. A number of prepared equilibrated homogenous membranes are available, as well as support for complex custom membranes.
  • New Ensemble Pharmacophore Generation protocol for pharmacophore modeling of large sets of active and inactive ligands. Optimized FitValue cut-offs in ensemble pharmacophores provide the best discrimination of active ligands from inactive ligands based on balanced accuracy.
  • New Interaction Pharmacophore Generation protocol to generate and validate hypotheses from ligand-receptor non-bond interactions.
  • Enhanced results of 3D QSAR pharmacophore generation validation and ligand profiling.
  • Enhanced antibody humanization workflow to specify V and J genes for both the H and L chains.
  • Enhanced protein preparation to handle multiple protein molecules, in parallel.
  • Updated PharmaDB with 16,034 entries, 4782 proteins and 6326 ligands.
  • New support for GOLD covalent ligand docking.
  • Enhanced 2D binding sites diagram with nucleic acid-ligand complexes.

System Requirements for Discovery Studio 2020

What's New in Discovery Studio 2020

Watch the on-demand webinar: What’s New in Discovery Studio 2020

With Discovery Studio you can:

  • Investigate and test hypotheses in silico prior to costly experimental implementation, thus reducing the time and expense involved in bringing products to market
  • Drive scientific exploration from target identification to lead optimization with a wealth of trusted life science modeling and simulation tools
  • Leverage an open and scalable platform to automate processes, create and deploy custom workflows, and integrate data types, databases, and third-party or in-house tools
  • Enhance personal productivity and boost team collaboration by enabling researchers to share data and make better informed decisions

Read the BIOVIA Discovery Studio Datasheet

Citations and Acknowledgements

We love to hear about Discovery Studio being used in new and interesting ways. If you want to cite the use of a BIOVIA Software product in a publication, we recommend the following format:

Ref. Dassault Systèmes BIOVIA, Discovery Studio Modeling Environment, Release 2017, San Diego: Dassault Systèmes, 2016.

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